Why Store My Immune Cells Now?

What can I use my immune cells for?

The average person’s likelihood of a cancer diagnosis is about 33 percent. However, thanks in part to the development of T-cell immunotherapies, there are now anti-cancer treatments that rely on a patient’s own immune cells. One such treatment, known as chimeric antigen receptor T (CAR T) cell therapy, is FDA approved for B-cell lymphoma and other blood cancers. There are also developments being made in dendritic cell (DC) therapy for malignancies such as prostate cancer.

Why bank now?

There are three key scientific reasons that one should bank their immune cells while they are still young and healthy.

1

The body’s immune system decays over age. The effects of aging on the immune system are manifest at multiple levels that include reduced production of B and T cells in bone marrow and thymus and diminished function of mature lymphocytes in secondary lymphoid tissues. As a result, elderly individuals do not respond to immune challenge as robustly as the young

2

The immune system is one of the most vulnerable target during cancer treatment. Compounded with the use of chemotherapy, radiotherapy, a patient’s immune system is severely damaged and has little chance to recover before starting immunotherapy

3

In many cases of advanced cancer, cancer cells will enter circulation, invade and interfere with the body’s natural production of immune cells, making the system less “pure and healthy”. As a result, many cancer patients fail to obtain enough healthy T-cells to allow the production of enough effector cells (such as CAR-T cells) for treatment.

Age reduction of immune cells

It is long been know that the body’s immune system decays over age. Storing immune cells while the body is still young and healthy ensures that patients will have access to the best quality cells later in life.

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Disclaimer: The use of cord blood and immune cells is determined by the treating physician and manufacturer of the final products and is influenced by many factors, including the patient's medical condition, the characteristics of the sample, and whether the immune cells should be further modified or expanded. Cord blood has established uses in transplant medicine; however, its use in regenerative medicine is still being researched. There is no guarantee that potential medical applications being studied in the laboratory or clinical trials will become available. Cord tissue use is still in early research stages, and there is no guarantee that treatments using cord tissue will be available in the future. Cord tissue is stored whole. Additional processing prior to use will be required to extract and prepare any of the multiple cell types from cryopreserved cord tissue. Immune cells has established uses in certain blood cancer treatment; however, its use in solid cancer is still being researched. There is no guarantee that treatments being studied in the laboratory, clinical trials, or other experimental treatments will be available in the future.

HealthBanks cryopreserves immune cells that have been collected from an individual for potential future cellular therapy use. HealthBanks does not provide medical advice, treatment or care. The use of cryopreserved cells for future immunotherapies is not guaranteed. Much is yet unknown about the future of immunotherapy and the immune cells that have been cryopreserved. The use of cryopreserved cells by commercial manufacturers for CAR-T therapy production is not currently approved by the FDA. There is active research ongoing, however, there is no guarantee that your cryopreserved cells will have a future therapeutic use. Only your health care professional can help you evaluate whether your cells might be used and if so, how they might be used. HealthBanks and its shareholders, directors, officers, agents, employees, affiliates, network of providers and provider facilities, will not be liable to you or any other party for claims relating to sample collection or if your cells cannot be used, or if any harm, injury, damage or loss results from the use of your cells. For more information, please refer to HealthBanks Service Agreement.