With 2022 coming to a close, we thought it would be interesting for our readers to take a look down the memory lane of 2022 & revisit eye-catching articles, journal entries & research papers we bookmarked over the past 12 months. Taking the first step to bank your newborn’s umbilical cord blood stem cells or your own immune cells unlocks the potential for using them in the future. With the emerging cell & gene therapy field advancing quickly with amazing preliminary results using stem cells & immune cells for treating diseases, we thought it would great to show a few articles that caught our eye.
2022 News Highlights
January 7, 2022: TED Talk: Jennifer Doudna: What does CRISPR mean for the future of human evolution?
https://www.npr.org/2022/01/07/1071067052/jennifer-doudna-what-does-crispr-mean-for-the-future-of-human-evolution
February 21, 2022: FDA Designates CT103A, CAR T-cell Therapy, an Orphan Drug
https://myelomaresearchnews.com/news/fda-designates-ct103a-car-t-cell-therapy-an-orphan-drug/
February 16, 2022: Researchers report third case of HIV remission after stem cell transplant using umbilical cord blood
https://www.cnn.com/2022/02/15/health/hiv-third-person-remission/index.html
February 25, 2022: Immune System ‘Reset’ by Stem Cell Transplant
March 23, 2022: SCIENTISTS SAY BRAIN IMPLANT LET COMPLETELY PARALYZED MAN COMMUNICATE AGAIN
https://futurism.com/neoscope/scientists-brain-implant-paralyzed-man-communicate
March 23 2022: Chinese, int’l scientists breed youngest human cells in vitro for organ regeneration
April 4, 2022: Researchers discover new cell type in human lung with regenerative properties
https://phys.org/news/2022-04-cell-human-lung-regenerative-properties.html
April 14, 2022: Rancho Cordova Company ThermoGenesis Aims To Make Life-Saving Cancer Treatment More Affordable
https://www.cbsnews.com/sacramento/news/rancho-cordova-thermogenesis-cancer-treatment/
May 29, 2022: ThermoGenesis, manufacturer of AXP, PXP, BioArchive, announce new 36,000 sq.ft GMP-compliant suite which will host 12 cleanrooms for cell & gene therapy industry.
June 28, 2022: Discovery Points to Better Treatments for Brain Tumors
https://newsroom.uvahealth.com/2022/06/28/discovery-points-to-better-treatments-for-brain-tumors/
July 20, 2022: 10 Years Later, Teen Is Still Cured from Cancer After Groundbreaking Therapy: ‘It’s a Miracle I’m Alive’
August 4, 2022: First Detailed Map of Immune System Connections Reveals Therapeutic Opportunities
August 17, 2022: FDA Approves First Cell-Based Gene Therapy to Treat Adult and Pediatric Patients with Beta-thalassemia Who Require Regular Blood Transfusions
August 24, 2022: RASA2 ablation in T cells boosts antigen sensitivity and long-term function in T cell therapies for cancer treatment.
https://www.nature.com/articles/s41586-022-05126-w
August 24, 2022: California Department of Public Health awards UC Davis $15.7M to manage Cancer Registry
August 24, 2022: Pioneering stem-cell trials in Japan report promising early results
https://www.nature.com/articles/d41586-022-02232-7
August 25, 2022: ‘Synthetic’ embryo with brain and beating heart grown from stem cells by Cambridge scientists
https://www.cam.ac.uk/stories/model-embryo-from-stem-cells
August 30, 2022: Rancho Cordova company using people’s cells to cure future diseases
September 13, 2022: The blood stem cell research that could change medicine of the future: microfluidic device that emulated an embryo’s heartbeat and blood circulation
https://phys.org/news/2022-09-blood-stem-cell-medicine-future.html
September 13, 2022: Inducible VIPER CAR-T Immunotherapy Uses Approved Drug to Turn Cells On or Off
September 19 2022: First time in India: Stem cell therapy to treat knee osteoarthritis
September 21, 2022: CAR T-Cell Therapy completely cures autoimmune diseases in several patients.
September 23, 2022: Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study
https://www.nature.com/articles/s41422-022-00721-y
September 26, 2022: Armored CAR T Cells Break Through Immune Suppression in Solid Tumors
September 26, 2022: Targeting Leukemia with T Cells That Avoid Self-Destruction
September 28, 2022: MSCs as “Therapeutic Workhouses” in the Era of Regenerative Medicine
https://bioinformant.com/mesenchymal-stem-cells-msc/
September 29, 2022: FDA grants orphan drug status to CAR-T cell immunotherapy candidate
September 2022: Cryopreserved allogeneic mesenchymal stem cells enhance wound repair in full thickness skin wound model and cattle clinical teat injuries
https://www.sciencedirect.com/science/article/abs/pii/S2452318622000241?via%3Dihub
https://www.frontiersin.org/articles/10.3389/fcell.2022.910592/full
October 5, 2022: Is Storing Your Immune Cells Really Worth It?
https://bioinformant.com/immune-cell-banking/
October 6, 2022: World’s first stem cell treatment for spina bifida delivered during fetal surgery
October 12, 2022: Gut microbiome modulates CAR-T cell therapy-related responses
https://www.miragenews.com/gut-microbiome-modulates-car-t-cell-therapy-872552/
October 18, 2022: Science saved his life at 21, and now this Trojan is on a mission.
https://news.usc.edu/202762/use-stem-cell-student-sheldon-ding/
October 22, 2022: Combined Transplantation of Human MSCs and ECFCs Improves Cardiac Function and Decrease Cardiomyocyte Apoptosis After Acute Myocardial Infarction
https://link.springer.com/article/10.1007/s12015-022-10468-z
October 24, 2022: T-cells treated by Turn Biotechnologies show increased cancer-killing effectiveness
October 28, 2022: Researchers at University Hospitals create a breakthrough in CAR-T cell therapy production (24-48 hours) for cancer patients versus 5-8 weeks previously.
October 28, 2022: cell grafts and rehabilitation combined boost spinal cord injury results
https://www.sciencedaily.com/releases/2022/10/221028121015.htm
November 2, 2022: Children with leukaemia were successfully treated with first-in-human “universal” CRISPR-edited T-cells
November 3, 2022: The effects of mesenchymal stromal cells and platelet-rich plasma treatments on cutaneous wound healing
https://link.springer.com/article/10.1007/s00403-022-02451-y
November 8, 2022: Engineered T cells to treat lupus arrive on the scene
https://www.nature.com/articles/d41586-022-03563-1
November 10, 2022: Blood Stem Cell Transplant Could Reboot Immune System in Multiple Sclerosis Patients
https://neurosciencenews.com/blood-stem-cell-multiple-sclerosis-21816/
November 14, 2022: How researchers used CRISPR gene editing to send immune cells after cancer
https://arstechnica.com/science/2022/11/gene-editing-used-in-new-clinical-trial-against-cancer/
December 8, 2022: Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in patients with Advanced Melanoma: progression-free survival was significantly longer among those who received TIL therapy than among those who received ipilimumab.
https://www.nejm.org/doi/full/10.1056/NEJMoa2210233
December 14, 2022: A Revolutionary Therapy Cures 13-Year-Old Girl’s Incurable Cancer
December 2022: Mesenchymal stem cell therapy: A review of clinical trials for multiple sclerosis
https://www.sciencedirect.com/science/article/pii/S2352320422000669
With 2022 coming to a close, we thought it would be interesting for our readers to take a look down … 2022 News Recap: A culmination of interesting news over the past 12 months.
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